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Haldi and Gobhi can keep prostate cancer at bay Washington: Adding haldi to your vegetables while cooking is not only good for enhancing its taste, but also very effective at the prevention and treatment of prostate cancer, say researchers. The scientists tested turmeric, also known as curcumin, along with phenethyl isothiocyanate (PEITC), a naturally occurring substance particularly abundant in a group of vegetables that includes watercress, cabbage, winter cress, broccoli, Brussels sprouts, kale, cauliflower, kohlrabi and turnips. The team from the Rutgers' Ernest Mario School of Pharmacy noted that in contrast to the high incidence of prostate cancer in the United States, the incidence of the disease was very low in India, which has been attributed to the dietary consumption of large amounts of plant-based foods rich in phytochemicals, ie nonnutritive plant chemicals that have protective or disease- preventive properties. For
the purposes of their study, researchers used mice bred so that their
immune systems would not reject foreign biological material, and injected
the mice with cells from human prostate cancer cell lines to grow tumors
against which the compounds could be tested. They injected the mice with
curcumin or PEITC, alone or in combination, three times a week for four
weeks, beginning a day before the introduction of the prostate cancer
cells. They found the injections significantly retarded the growth of
cancerous tumors, and by using PEITC and curcumin in tandem, it produced
even stronger effects. The group went on to evaluate the therapeutic potential
of curcumin and PEITC in mice with well-established tumors, and the results
showed that PEITC or curcumin alone had little effect, whereas the combination
of curcumin and PEITC significantly reduced tumor growth. "The bottom
line is that PEITC and curcumin, alone or in combination, demonstrate
significant cancer-preventive qualities in laboratory mice, and the combination
of PEITC and curcumin could be effective in treating established prostate
cancers," said Ah-Ng Tony Kong, a professor of pharmaceutics at Rutgers,
The State University of New Jersey.
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